Sufanilamide, prepared using DEG (a poison) as solvent resulted in the death of more than 100 people in the USA in 1937. This incid

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birth deformities in more than 10,000 children in late 1950s and early 1960s. This incident led to the Kefauver-Harris Amendment in USA-it is a 1962 amendment to the Federal Food, Drug and cosmetic act.